Nuclear lamins are important structural and functional proteins in mammalian cells, but little Satchels is known about the mechanisms and cofactors that regulate their traffic into the nucleus.Here, we demonstrate that trafficking of lamin A, but not lamin B1, and its assembly into the nuclear envelope are regulated by sorting nexin 6 (SNX6), a maj
Flaviviruses are enveloped viruses which include human pathogens that are predominantly transmitted by mosquitoes and ticks.Some, such as dengue virus, exhibit the phenomenon of antibody-dependent enhancement (ADE) of disease, making vaccine-based routes of fighting infections problematic.The pH-dependent conformational change of the envelope (E) p
The conservation status of relic melanistic lizard species occurring in the Saldanha- Langebaan area has been investigated.A contact zone between one melanistic form and a closely related non-melanistic form cane has been examined in detail.Apart from melanis- tic populations of the girdled lizards, Cordylus niger and C.polywnus, a melanistic morph
The language is very dynamic, consequently, there are great hallenges for the framing of words into classes.That happens because the understanding generated by a particular word is linked to the context, and also anchored in syntactic and semantic roles that are able to play in the Ironing Stations environment of linguistic usage.In this article, w
Barley (Hordeum vulgare L.) is a multipurpose crop that can be harvested as grain or cut prior to maturity for use as forage.Fusarium head blight (FHB) is a devastating disease of barley that reduces quality of grain.FHB can also result in the accumulation of mycotoxins such as deoxynivalenol (DON).Breeding FHB resistant varieties has been a long-t